GONADOTROPHINS AND TESTOSTERONE IN THE XYY SYNDROME

Serum gonadotrophins in Down's syndrome.

Serum levels of follicle stimulating hormone (FSH) and luteinising hormone (LH) in institutionalised male patients with Down's syndrome (DS) have been found to be significantly higher than in age matched controls from the same institution. This difference is found in patients both under and over 30 years of age with respect to FSH levels, but the increase in LH levels is confined to patients wi...

Psychiatry sociopathy and the XYY chromosome syndrome.

Effect of Metronidazole on Spermatogenesis, Plasma Gonadotrophins and Testosterone in Male Rats

Metronidazole and it’s derivatives are drugs that have both antiprotozoal and anti bacterial effect.The reproductive toxicity of metronidazole has been shown in some studies. To investigate the effect of metronidazole on spermatogenesis in adult male rats, this study was designed. Eighteen wistar male rats (70-90days old) were randomly divided into three groups. Animals in group I (Control grou...

XYY syndrome, and XYY-XXYY mosaicism also showing features of Klinefelter's syndrome.

Both the 48,XXYY and the 47,XYY chromosome anomalies are now well-recognized conditions following the first reports by Muldal and Ockey (1960) of the XXYY genotype, and Sandberg et al. (1961) who described an XYY male. This paper presents the findings in 2 patients with 47,XYY/48,XXYY mosaicism, and one patient with the 47,XYY anomaly, discovered among 250 men in a comprehensive hospital for th...

XYY Males and Testosterone Excretion TABLE I GROUPS 1 AND 2 : RAMPTON DETAINEES Testosterone

The incidence of males with an XYY chromosome complement in a maximum security hospital was found to be 3% (Jacobs et al., 1965). These males were exceptionally tall, and it was found that 1 in 3 of the men of over 6 ft. (183 cm.) in this hospital had an XYY chromosome constitution. This very high incidence in an over-6 ft. group was confirmed in a special hospital for the subnormal (Casey et a...